Welcome to the Drögemöller Lab

Our lab focuses on using genomics and computational analyses to develop safer and more effective treatments

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Drögemöller Lab

University of Manitoba

About

The Drögemöller Lab uses large-scale genomic and computational analyses to guide the development of novel treatment strategies that offer maximum benefit and minimal harm.

This research is focused specifically on vulnerable and understudied populations (e.g. pediatric and maternal populations) as therapeutic agents are often not designed and tested with these patients in mind.

Interests

  • Genomics
  • Bioinformatics
  • Pharmacogenomics
  • Precision Medicine

Meet the Team

Principal Investigator

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Britt Drögemöller
Assistant Professor
Canada Research Chair
in Pharmacogenomics and Precision Medicine

Lab members

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Mackenzie Wilke
MSc Student

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Samah Ahmed
MSc Student

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Sarah Lyle
Co-op Student

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Urim Iyasere
Summer Research Student

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Vaibhav
Summer Research Student

Alumni

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Danielle Johnson
Mitacs-Globalink UK-Canada PhD exchange student

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Britt Drögemöller
Assistant Professor
Canada Research Chair
in Pharmacogenomics and Precision Medicine

Principal Investigator

Dr. Britt Drögemöller is an Assistant Professor in the Department of Biochemistry & Medical Genetics at the University of Manitoba. Dr. Drögemöller holds a Canada Research Chair in Pharmacogenomics and Precision Medicine and is appointed as a Research Scientist at The Children’s Hospital Foundation of Manitoba (CHRIM) and an Adjunct Scientist at the CancerCare Manitoba Research Institute.

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Mackenzie Wilke
MSc Student

MSc student

MacKenzie Wilke is a MSc student in the Department of Biochemistry & Medical Genetics at the University of Manitoba. MacKenzie has graduated with her BSc (Hons) in Genetics from the University of Manitoba in 2020. She completed an undergraduate thesis on identifying genes associated with autism spectrum disorder through Hardy-Weinberg disequilibrium and her MSc project will focus on developing a polygenic risk score in order to aid with the prediction and prevention of cisplatin-induced ototoxicity.

Interests

  • Bioinformatics
  • Evolutionary Genetics
  • Rare Diseases
  • Pharmacogenomics & Precision Medicine
  • Dancing

Education

  • MSc in Computational Biology, 2020-2022

    University of Manitoba, Canada

  • BSc Hons in Genetics, 2015-2020

    University of Manitoba, Canada

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Samah Ahmed
MSc Student

MSc student

Samah Ahmed is a MSc student in the Department of Biochemistry & Medical Genetics at the University of Manitoba. Samah has graduated with her B.Pharm from the University of Khartoum in 2010. Her MSc project will focus on identifying genetic variants and genes involved in pathways underlying hearing through GWAS and scRNAseq analyses.

Interests

  • Bioinformatics
  • Pharmacogenomics and Precision Medicine
  • Public Health
  • Voice-Over

Education

  • MSc in Computational Biology, 2021 - 2023

    University of Manitoba, Canada

  • MSc in Molecular Medicine, 2012 - 2014

    University of Khartoum, Sudan

  • B.Pharm, 2005-2010

    University of Khartoum, Sudan

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Sarah Lyle
Co-op Student

Honours Student

Sarah is an undergrad student at the Univeristy of Manitoba currently pursing a Genetic Honours Co-op degree. Under the supervision of Dr. Drögemöller she is studying genetic variants associated with polycystic ovary syndrome and their role in treatment outcomes of patients.

Interests

  • Public Health
  • Epidemiology
  • Pharmacogenomics & Precision Medicine
  • Infectious Disease

Education

  • BSc Hons Co-op in Genetics, 2016-2021

    University of Manitoba, Canada

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Danielle Johnson
Mitacs-Globalink UK-Canada PhD exchange student

Mitacs-Globalink UK-Canada PhD exchange student

Danielle Johnson is a PhD student at the University of Liverpool, UK, who has been awarded a Mitacs Globalink internship in the Drögemöller lab. She previously completed her MRes at King’s College London and a BSc in Medical Sciences at the University of Exeter. She previously worked on the STAMPEDE trial at the Medical Research Council, London.

Interests

  • Trial design
  • Methodology
  • Pharmacogenetics

Education

  • PhD in pharmacogenetics, 2017-2021

    University of Liverpool, UK

  • BSc in Medical Sciences, 2010-2014

    University of Exeter, UK

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Vaibhav
Summer Research Student

Undergraduate Student

Vaibhav is an undergraduate student at the University of Manitoba pursuing a Major in Microbiology. He will be working under the supervision of Dr. Drögemöller, mining cisplatin-induced gene expression and cytotoxicity data to identify genes of relevance to cisplatin-induced ototoxicity.

Interests

  • Bioinformatics
  • Pharmacogenetics
  • Cancer cell biology

Education

  • BSc Majors in Microbiology, 2018-2021

    University of Manitoba, Canada

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Urim Iyasere
Summer Research Student

Undergraduate Student

Urim Iyasere is an undergraduate student at the Univeristy of Manitoba currently pursing a Genetic Hons Co-op degree. Urim’s summer project will focus on identifying genes that are relevant to cisplatin-induced ototoxicity.

Interests

  • Computational Biology
  • Pharmacogenomics & Precision Medicine
  • Bioinformatics & Biostatistics
  • Languages
  • Music

Education

  • BSc Hons Co-op in Genetics, 2018-2023

    University of Manitoba, Canada

News

Welcome to Samah Ahmed, who will be joining the lab as an MSc student!

Congrats on receiving the International Graduate Student Entrance Scholarship, Samah! Samah will be working on using single cell sequencing and GWAS to gain insight into the genomics of hearing loss traits.

Welcome to Urim Iyasere and Vaibhav, who will be joining the lab as summer students!

Congrats on receiving the CancerCare Manitoba Research Institute and Children’s Hospital Research Institute of Manitoba (CHRIM) Undergraduate Summer Studentships!

Congratulations to Sarah Lyle for completing her Genetics Honours project!

In addition to Sarah completing her Honours project focusing on the genetics of polycystic ovary syndrome, we are also thrilled that Sarah will be staying on in the lab as a Co-op student!

To celebrate everyone's hard work over the last couple of months we took part in a Heist

Thanks to some very clever people in the lab, we successfully completed this escape room game (despite “helpful” contributions from the PI)

Welcome to Danielle Johnson, who will be joining the lab as a Mitacs-Globalink UK-Canada PhD exchange student!

Danielle will be joining us remotely from the UK to perform a systematic review of the use of polygenic risk scores in the field of pharmacogenomics.

The Drögemöller and Wright labs receive Carnegie African Diaspora Fellowships for their Graduate Training and Collaborative Research in Neurogenomics and Precision Medicine application

This funding has been provided to support a collaboration between the University of Manitoba and Stellenbosch University in South Africa to develop (i) a genomics analysis pipeline for the improved diagnosis and treatment of neurological diseases in Manitoba and South Africa and (ii) workshops aimed at training graduate students in Neurogenomics & Precision Medicine at the University of Manitoba, Canada and Stellenbosch University, South Africa.

Recent Publications

Contact

Dr. Drögemöller is currently recruiting graduate students and postdoctoral fellows with expertise in genomics, bioinformatics, pharmacogenomics and precision medicine. Interested individuals should send a recent CV, along with a short cover letter explaining why they are interested in joining the lab.